{
  "created_at": "2026-09-11T03:38:41.299506+00:00",
  "label_type": "AI source assessment; independent human review pending",
  "model_predictions_seen": false,
  "selected_products": [
    {
      "drug_code": "74379",
      "din": "02258595",
      "brand_name": "HUMIRA",
      "query": "adalimumab"
    },
    {
      "drug_code": "80247",
      "din": "02316986",
      "brand_name": "XARELTO",
      "query": "rivaroxaban"
    },
    {
      "drug_code": "78924",
      "din": "02303922",
      "brand_name": "JANUVIA",
      "query": "sitagliptin"
    },
    {
      "drug_code": "69428",
      "din": "02245385",
      "brand_name": "SYMBICORT 100 TURBUHALER",
      "query": "SYMBICORT"
    }
  ],
  "product_rule": "Smallest numeric drug_code among MARKETED rows containing selected brand in approved 58,034-row DPD snapshot. Brands purposively selected across biologic, anticoagulant, diabetes oral drug and inhaled combination.",
  "study_rule": "First 20 relevance-ranked results of each prespecified ingredient/brand intervention query; discard any NCT found in prior accessible artifacts; sort remaining NCT IDs and select first 3. No matcher outcomes or support labels used.",
  "control_rule": "One additional prespecified unrelated-product pair per product: pair each product with the first selected study of the next query in the circular order HUMIRA→XARELTO→JANUVIA→SYMBICORT→HUMIRA. These are constructed mismatch controls, not naturally retrieved cases.",
  "limitations": [
    "Purposive small sample; no population representativeness or clinical gold standard",
    "New IDs relative to accessible scan only; global historical independence cannot be guaranteed",
    "Comparator-only ingredient occurrences are documented separately; comparators are not efficacy evidence for the selected product",
    "Missing source evidence is not a disproved relationship",
    "No causal, clinical safety or efficacy assessment"
  ],
  "release_id": "6b197660c54a2468082b1064a52c88aa813915ab0728ab92dd1b1f9c50dc0871",
  "dpd_index_sha256": "8ae898a26d878b3776c06bf42ee878062f64ca4b387b39af958c820bf8c1651b",
  "excluded_nct_count": 300,
  "exclusion_scan_sha256": "bf504f43885d62b5d9d2119a067b4ce6ea05cd239ae7eb1061285eb282dda0cc"
}